Where this is a non-indigenous species, eradication methods are often sought after. There are both biological and herbicidal solutions to the problem, but neither of them provide a solution which is both quick and long-lasting, because T. terrestris seeds remain viable for up to 37 years on average.
In smaller areas, puncture vine is best controlled with manual removal using a hoe to cut the plant off at its taproot. While this is effective, removing the entire plant by gripping the taproot, stem or trunk and pulling upward to remove the taproot is far more effective. This requires monitoring the area and removing the weed throughout the preseeding time (late spring and early summer in many temperate areas). This will greatly reduce the prevalence of the weed the following year. Mowing is not an effective method of eradication, because the plant grows flat against the ground.
Another avenue of physical eradication is to crowd out the opportunistic weed by providing good competition from favorable plants. Aerating compacted sites and planting competitive desirable plants including broad-leaved grasses such as St Augustine can reduce the impact of puncture vine by reducing resources available to the weed.